Research use only
ARA-290
For research use only. Not for human or animal use.
FOR RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL USE. This product is not a drug, food, cosmetic, or dietary supplement, and has not been evaluated or approved by the FDA for any use other than laboratory research. Not for diagnostic or therapeutic use. Sale is restricted to qualified research professionals and institutions.
What it is
ARA-290 (also discussed in the literature under the name cibinetide for the pyroglutamate form) is a short synthetic peptide. This listing is a research solid. It is a different molecule from erythropoietin.
Structure and sequence
Linear surface sequence reported by Brines et al.: QEQLERALNSS. The pyroglutamate form is a chemical variant of the N-terminus and should be confirmed on the certificate.
Molecular weight
Mass depends on whether the N-terminus is glutamine or pyroglutamate. Use the certificate of analysis for the lot mass.
What published research models study
The 2008 PNAS paper distinguishes this peptide from erythropoietic EPO-receptor homodimer signalling and maps binding toward an EPO-receptor / beta-common-receptor complex in the models those authors used. That is receptor and model context, not a catalog claim.
- Brines et al., PNAS, 2008. PMID 18676614
Storage and handling
Supplied as a lyophilized solid in a sealed vial unless the catalog row states another format. Recommended storage is −20 °C. Trained laboratory personnel should handle the vial with appropriate personal protective equipment. Identity, purity, salt form, and lot-specific notes belong on the certificate of analysis, which is available on request.
Catalog listing
ARA-290 in the research catalog
Latest published studies · How certificates are handled